Exclusive patented ingredient

The biotech active ingredient that strengthens your skin.

BIOME-RXCELL™: our patented ingredient that rebalances the microbiome and strengthens the skin barrier from the very first application.

The result? Healthier-looking skin, with fewer inflammations, fewer imperfections, and enhanced radiance. Visibly regenerated.

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PROVEN EFFICACY

Results proven by 4 clinical studies

RESULT 1
-30%
of S. aureus (pathogenic bacteria)
Fewer inflammations and imperfections.
Histogram analysis measured on a reconstructed human epidermis (RHE).
RESULT 2
+20%
of S. epidermidis (beneficial bacteria)
A balanced skin microbiome
Histogram analysis measured on a reconstructed human epidermis (RHE).
RESULT 3
+113%
of cellular respiration
The skin functions better. It appears more radiant.
In vitro tests – Cellular respiration (O₂/ATP) & cellular and mitochondrial metabolism.
RESULT 4
-22%
of oxidative stress
The skin helps combat signs of ageing caused by free radicals.
In vitro test – study of lipid peroxidation (oxidative stress).

Puréality est la seule marque au monde à encapsuler un prébiotique dans une cellule végétale.

  • Brevet - Patent

    BE 2020/0127

  • Supported by

    BPI FRANCE - INNOVATION R&D

  • They talk about us

    PREMIUM BEAUTY NEWS

THE FINDINGS OF OUR EXPERTS

Why is the skin becoming increasingly fragile?

You treat the symptoms, not the cause.

  • Imbalanced microbiome

    Daily aggressions disrupt your skin’s natural ecosystem.

  • Weakened skin barrier

    The skin no longer retains moisture and allows irritants to penetrate.

  • Overstimulation

    Actives that are sometimes too harsh and poorly combined can weaken the skin.

“82% of French people say they have sensitive skin.”

SYRES Laboratories. Sensitive skin: study of 20,000 French people, 2025

THE PURÉALITY SOLUTION

Biotech: clean beauty 3.0

A new generation of actives

The skin is an ally.

We use biotechnology to create more effective, natural, safe and sustainable cosmetic actives that work with it.

We start with the best of nature and enhance its full potential, with minimal impact on biodiversity.

Learn more about biotech
Photo du laboratoire Puréality dans les Alpes

THE PURÉALITY SCIENTIFIC COMMITTEE

BIOME-RXCELL™: a 100% French innovation 🇫🇷

The Puréality Scientific Committee, bringing together a biotech agency, the University of Bordeaux and INRAE, supports our innovation strategy and the development of plant-based molecules.

From this collaboration was born our patented active ingredient, BIOME-RXCELL™, developed over two years of R&D, which embodies our vision of skincare: strengthening the skin’s natural adaptive capabilities and rebalancing its microbiome.

Formulation charter

“We had to meet the demand for effectiveness while respecting expectations of naturalness and tolerance.”

Nicolas de Klebnikoff – Founder

The process

How it works

Puréality’s botanical biotechnology is based on the use of whole active plant cells, rather than plant extracts or isolated fractions. These active cells contain only the compounds and components that the plant would naturally produce.

  • Clean sourcing

    We take an active plant cell from Rhodiola rosea directly from the stem, without cultivation or alteration. Healthy and intact, it naturally multiplies in the laboratory.

  • Prebiotic encapsulation

    We encapsulate a prebiotic, an expert in balancing the skin microbiome, at the heart of Rhodiola rosea cells. This is how BIOME-RXCELL™ is created, our unique patented biotech active ingredient.

  • Revitalises and brightens the complexion

    This biomimetic active reproduces the skin’s natural mechanisms, ensuring excellent tolerance. Its benefits are delivered deep within the skin.

  • Active cell of Rhodiola rosea…

    We chose Rhodiola rosea, an adaptogenic plant, for its ability to help the skin adapt to stress. Naturally energising and rich in antioxidants, it boosts skin vitality and resilience.

  • Ingrédient céramides

    … + Prebiotic

    We selected a prebiotic that acts as a substrate for beneficial microorganisms, helping to support microbiome balance and the skin’s natural defences.

  • Ingrédient panthénol

    = BIOME-RXCELL™ active ingredient

    While most brands combine existing actives into complexes, we chose to develop our own unique and novel active ingredient, combining high tolerance, potency and efficacy.

The benefits of BIOME-RXCELL™

What our active does for your skin

SKIN MICROBIOME
SKIN MICROBIOME
Balances beneficial and harmful bacteria
PROTECTION
PROTECTION
Strengthens the skin barrier
+113 %
+113 %
Improves cellular oxygenation
ANTI-INFLAMMATORY
ANTI-INFLAMMATORY
Soothes inflammation
RADIANCE
RADIANCE
Boosts natural radiance
RESILIENCE
RESILIENCE
Improves resilience to stress

Give your skin what it has never had

BIOME-RXCELL™ is not just another active. It’s a complex technology that enhances the skin’s natural ability to adapt.

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